Continuing weight loss may deteriorate into wasting, a vaguely defined condition called cachexia.[30] Cachexia differs from starvation in part because it involves a systemic inflammatory response.[30] It is associated with poorer outcomes.[25][30][31] In the advanced stages of progressive disease, metabolism can change so that they lose weight even when they are getting what is normally regarded as adequate nutrition and the body cannot compensate. This leads to a condition called anorexia cachexia syndrome (ACS) and additional nutrition or supplementation is unlikely to help.[27] Symptoms of weight loss from ACS include severe weight loss from muscle rather than body fat, loss of appetite and feeling full after eating small amounts, nausea, anemia, weakness and fatigue.[27]

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Women have, throughout history, made contributions to science, literature and art. One area where women have been permitted most access historically was that of obstetrics and gynecology (prior to the 18th century, caring for pregnant women in Europe was undertaken by women; from the mid 18th century onwards medical monitoring of pregnant women started to require rigorous formal education, to which women did not generally have access, therefore the practice was largely transferred to men).[95][96]

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